Scientific References for UpCell Surface

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Collier TO, Anderson JM, Kikuchi A, Okano T. Adhesion behavior of monocytes, macrophages, and foreign body giant cells on poly (N-isopropylacrylamide) temperature-responsive surfaces. J. Biomed. Mater. Res. 2002; 59:136-143.

Gordon IO, Freedman RS. Defective antitumor function of monocyte-derived macrophages from epithelial ovarian cancer patients. Clin. Cancer Res. 2006; 12:1515-1524.

Harimoto M, Yamato M, Hirose M, Takahashi C, Isoi Y, Kikuchi A, Okano T. Novel approach for achieving double-layered cell sheets co-culture: overlaying endothelial cell sheets onto monolayer hepatocytes utilizing temperature-responsive culture dishes. J. Biomed. Mater. Res. 2002; 62:464-470.

Hasegawa M, Yamato M, Kikuchi A, Okano T, Ishikawa I. Human periodontal ligament cell sheets can regenerate periodontal ligament tissue in an athymic rat model. Tissue Eng. 2005; 11:469-478.

Hata H, Matsumiya G, Miyagawa S, Kondoh H, Kawaguchi N, Matsuura N, Shimizu T, Okano T, Matsuda H, Sawa Y. Grafted skeletal myoblast sheets attenuate myocardial remodeling in pacing-induced canine heart failure model. J. Thorac. Cardiovasc. Surg. 2006; 132:918-924.

Hobo K, Shimizu T, Sekine H, Shin’oka T, Okano T, Kurosawa H. Therapeutic angiogenesis using tissue engineered human smooth muscle cell sheets. Arterioscler. Thromb. Vasc. Biol. 2008; 28:637-643.

Ishii K., Fumoto T, Iwai K, Takeshita S, Ito M, Shimohata N, Aburatani H, Taketani S, Lelliotti CJ , Vidal-Puig A & Ikeda K. Coordination of PGC-1b and iron uptake in mitochondrial biogenesis and osteoclast activation. Ishii et al. 2009. Nature Medicine 15,3.

Kanzaki M, Yamato M, Hatakeyama H, Kohno C, Yang J, Umemoto T, Kikuchi A, Okano T, Onuki T. Tissue engineered epithelial cell sheets for the creation of a bioartifi cial trachea. Tissue Eng. 2006; 12:1275-1283.

Kanzaki M, Yamato M, Yang J, Sekine H, Kohno C, Takagi R, Hatakeyama H, Isaka T, Okano T, Onuki T. Dynamic sealing of lung air leaks by the transplantation of tissue engineered cell sheets. Biomaterials 2007; 28:4294-4302.

Kubota A, Nishida K, Yamato M, Yang J, Kikuchi A, Okano T, Tano Y. Transplantable retinal pigment epithelial cell sheets for tissue engineering. Biomaterials 2006; 27:3639-3644.

Kushida A, Yamato M, Konno C, Kikuchi A, Sakurai Y, Okano T. Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fi bronectin matrix from temperature-responsive culture surfaces. J. Biomed. Mater. Res. 1999; 45:355-362.

Kushida A, Yamato M, Isoi Y, Kikuchi A, Okano T. A noninvasive transfer system for polarized renal tubule epithelial cell sheets using temperatureresponsive culture dishes. Eur. Cell Mater. 2005;10:23-30.

Miyahara Y, Nagaya N, Kataoka M, Yanagawa B, Tanaka K, Hao H, Ishino K, Ishida H, Shimizu T, Kangawa K, Sano S, Okano T, Kitamura S, Mori H. Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nat. Med. 2006; 12:459-465.

Nakajima K, Honda S, Nakamura Y, López- Redondo F, Kohsaka S, Yamato M, Kikuchi A, Okano T. Intact microglia are cultured and noninvasively harvested without pathological activation using a novel cultured cell recovery method. Biomaterials 2001; 22:1213-1223.

Nandkumar MA, Yamato M, Kushida A, Konno C, Hirose M, Kikuchi A, Okano T. Two-dimensional cell sheet manipulation of heterotypically cocultured lung cells utilizing temperature-responsive culture dishes results in long-term maintenance of differentiated epithelial cell functions. Biomaterials 2002; 23:1121-1130.

Nishida K, Yamato M, Hayashida Y, Watanabe K, Maeda N, Watanabe H, Yamamoto K, Nagai S, Kikuchi A, Tano Y, Okano T. Functional bioengineered corneal epithelial sheet grafts from corneal stem cells expanded ex vivo on a temperature-responsive cell culture surface. Transplantation 2004; 77:379-385.

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Okano T, Nakajima Y. Engineering functional two- and three-dimensional liver systems in vivo using hepatic tissue sheets. Nat. Med. 2007; 13:880-885.

Ohki T, Yamato M, Murakami D, Takagi R, Yang J, Namiki H, Okano T, Takasaki K. Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine model. Gut 2006; 55:1704-1710.

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Sekine H, Shimizu T, Yang J, Kobayashi E, Okano T. Pulsatile myocardial tubes fabricated with cell sheet engineering. Circulation 2006; 114 (Suppl):I87-I93.

Sekiya S, Shimizu T, Yamato M, Kikuchi A, Okano T. Bioengineered cardiac cell sheet grafts have intrinsic angiogenic potential. Biochem. Biophys. Res. Commun. 2006; 341:573-582.

Shimizu T, Yamato M, Isoi Y, Akutsu T, Setomaru T, Abe K, Kikuchi A, Umezu M, Okano T. Fabrication of pulsatile cardiac tissue grafts using a novel 3Dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces. Circ. Res. 2002; 90:e40-e48.

Shimizu T, Sekine H, Isoi Y, Yamato M, Kikuchi A, Okano T. Long-term survival and growth of pulsatile myocardial tissue grafts engineered by the layering of cardiomyocyte sheets. Tissue Eng. 2006; 12:499-507.

Shiroyanagi Y, Yamato M, Yamazaki Y, Toma H, Okano T. Transplantable urothelial cell sheets harvested non-invasively from temperature responsive culture surfaces by reducing temperature. Tissue Eng. 2003; 9:1005-1012.

Sumide T, Nishida K, Yamato M, Ide T, Hayashida Y, Watanabe K, Yang J, Kohno C, Kikuchi A, Maeda N, Watanabe H, Okano T, Tano Y. Functional human corneal endothelial cell sheets harvested from temperature-responsive culture surfaces. FASEB J. 2006; 20:392-394.

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Yamato M, Utsumi M, Kushida A, Konno C, Kikuchi A, Okano T. Thermo-responsive culture dishes allow the intact harvest of multilayered keratinocyte sheets without dispase by reducing temperature. Tissue Eng. 2001; 7:473-480.

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